Invitrogen™ Chitotriosidase Monoclonal Antibody (1D9G2,1D9G4,2B4G3)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA515482

Catalog No. PIMA515482

Description

MA5-15482 targets CHIT1 in indirect ELISA, WB applications and shows reactivity with Human samples. The MA5-15482 immunogen is purified recombinant fragment of CHIT1 (aa22-137) expressed in E. Coli..

Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.

Specifications

• Antigen: Chitotriosidase
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: Ascites with 0.03% sodium azide
• Gene Accession No.: Q13231
• Gene Symbols: CHIT1
• Immunogen: Purified recombinant fragment of CHIT1 (aa22-137) expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 1118
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Western Blot
• Clone: 1D9G2,1D9G4,2B4G3, 1D9G4, 2B4G3
• Conjugate: Unconjugated
• Gene: CHIT1
• Gene Alias: 2300002L19Rik; CHI3; CHIT; Chit1; CHITD; chitinase 1; chitinase 1 (chitotriosidase); chitinase-1; Chitotriosidase; Chitotriosidase-1; EC 3.2.1.14; FLJ00314; MGC125322; plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

Safety and Handling

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