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Invitrogen™ Chitotriosidase Polyclonal Antibody
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Catalog No. PIPA547510
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100 μg
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PIPA547510 100 μg
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Catalog No. PIPA547510 Supplier Invitrogen™ Supplier No. PA547510
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Goat Polyclonal Antibody

Reconstitute at 0.2 mg/mL in sterile PBS.

Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Chitotriosidase
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene CHIT1
Gene Accession No. Q13231
Gene Alias 2300002L19Rik; CHI3; CHIT; Chit1; CHITD; chitinase 1; chitinase 1 (chitotriosidase); chitinase-1; Chitotriosidase; Chitotriosidase-1; EC 3.2.1.14; FLJ00314; MGC125322; plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase
Gene Symbols CHIT1
Host Species Goat
Immunogen Mouse myeloma cell line NS0-derived recombinant human Chitotriosidase/CHIT1 Ala22-Asn466.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1118
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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