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Invitrogen™ Chitotriosidase Polyclonal Antibody
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Catalog No. PIPA582395
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100 μL
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PIPA582395 100 μL
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Catalog No. PIPA582395 Supplier Invitrogen™ Supplier No. PA582395
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: FDDVESFKTK VSYLKQKGLG GAMVWALDLD DFAGFSCNQG RYPLIQTLRQ ELSLPYLPSG TPELEVPKPG QPSEPEHGPS PGQDTFCQGK ADGLYPNPRE RSSFYSCAAG RLFQQSCPTG LVFSNSCKCC TWN Highest antigen sequence indentity to the following orthologs: Rat - 73%, Mouse - 70%.

Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Chitotriosidase
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CHIT1
Gene Accession No. Q13231
Gene Alias 2300002L19Rik; CHI3; CHIT; Chit1; CHITD; chitinase 1; chitinase 1 (chitotriosidase); chitinase-1; Chitotriosidase; Chitotriosidase-1; EC 3.2.1.14; FLJ00314; MGC125322; plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase
Gene Symbols CHIT1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CHIT1. Recombinant protein control fragment (Product #RP-90229).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1118
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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