Chloroacetic anhydride, 97%

Description

CAS: 541-88-8 | C4H4Cl2O3 | 170.97 g/mol

Chloroacetic anhydride has been used in the synthesis of 3,3?-bis(sulfonato)-4,4?-bis(chloroacetamido)azobenzene (BSBCA), a water-soluble, thiol-reactive and photo-switchable cross-linker, D,L-7-azatryptophan, 2-methyl-[3,4-di-O-acetyl-6-O-(chloroacetyl)-1,2-dideoxy-α-D-glucopyrano]-[2?,1?:4,5]-2-oxazoline.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Chloroacetic anhydride has been used in the synthesis of 3,3′-bis(sulfonato)-4,4′-bis(chloroacetamido)azobenzene (BSBCA), a water-soluble, thiol-reactive and photo-switchable cross-linker, D,L-7-azatryptophan, 2-methyl-[3,4-di-O-acetyl-6-O-(chloroacetyl)-1,2-dideoxy-α-D-glucopyrano]-[2′,1′:4,5]-2-oxazoline.

Solubility
Freely soluble in ether, chloroform. Slightly soluble in benzene. Insoluble in cold ligroin

Notes
Moisture sensitive. Incompatible with oxidizing agent, bases, amines, alcohols, water/ moisture.

Specifications

Chemical Identifiers

• CAS: 541-88-8
• Molecular Formula: C4H4Cl2O3
• Molecular Weight (g/mol): 170.97
• MDL Number: MFCD00000929
• InChI Key: PNVPNXKRAUBJGW-UHFFFAOYSA-N
• Synonym: chloroacetic anhydride, chloracetic anhydride, monochloroacetic acid anhydride, 2-chloroacetic anhydride, chloroacetic acid anhydride, chloroacetyl anhydride, acetic acid, chloro-, anhydride, unii-8q7txh7r5f, monochloroacetic anhydride, 8q7txh7r5f
• PubChem CID: 10946
• IUPAC Name: (2-chloroacetyl) 2-chloroacetate
• SMILES: ClCC(=O)OC(=O)CCl

• Melting Point: 56°C to 59°C
• Boiling Point: 110°C to 112°C (10 mmHg)
• Flash Point: 143°C (289°F)
• Quantity: 100 g
• UN Number: UN3261
• Beilstein: 774533
• Sensitivity: Moisture sensitive
• Merck Index: 14,2113
• Solubility Information: Freely soluble in ether, chloroform; Slightly soluble in benzene; Insoluble in cold ligroin
• Formula Weight: 170.98
• Percent Purity: 97%
• Chemical Name or Material: Chloroacetic anhydride

Safety and Handling

Hazard Category	H301+H311+H331-H314-H335
Hazard Statement	GHS H Statement H300-H314-H318 Fatal if swallowed. Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statement	P260-P264b-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S.
EINECSNumber	208-794-2
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only