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Invitrogen™ CHM Polyclonal Antibody
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Catalog No. PIPA551870
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100 μL
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PIPA551870 100 μL
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Catalog No. PIPA551870 Supplier Invitrogen™ Supplier No. PA551870
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SRKDKTIQHV EVFCYASQDL HEDVEEAGAL QKNHALVTSA NSTEAADSAF LPTEDESLST MSCEMLTEQT PSSDPENALE VNGAEVTGEK ENHCDDKTCV PSTSAEDMSE NVPIAEDTTE QPKKNRITYS QIIKEG Highest antigen sequence identity to the following orthologs: Mouse - 58%, Rat - 66%.

Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B composed of RABGGTA and RABGGTB, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CHM
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CHM
Gene Accession No. P24386
Gene Alias CHM; CHM, Rab escort protein 1; choroideraemia protein homolog; choroideremia (Rab escort protein 1); Choroideremia protein; Choroideremia protein homolog; choroidermia; choroidermia (RAB escort protein 1); DXS540; GGTA; HSD-32; Rab escort protein 1; rab proteins geranylgeranyltransferase component A 1; REP1; REP-1; TCD; TCD protein
Gene Symbols CHM
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CHM. Recombinant protein control fragment (Product #RP-92170).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1121
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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