Invitrogen™ CHM Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA551870

Catalog No. PIPA551870

Description

Immunogen sequence: SRKDKTIQHV EVFCYASQDL HEDVEEAGAL QKNHALVTSA NSTEAADSAF LPTEDESLST MSCEMLTEQT PSSDPENALE VNGAEVTGEK ENHCDDKTCV PSTSAEDMSE NVPIAEDTTE QPKKNRITYS QIIKEG Highest antigen sequence identity to the following orthologs: Mouse - 58%, Rat - 66%.

Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B composed of RABGGTA and RABGGTB, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation.

Specifications

• Antigen: CHM
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CHM
• Gene Alias: CHM; CHM, Rab escort protein 1; choroideraemia protein homolog; choroideremia (Rab escort protein 1); Choroideremia protein; Choroideremia protein homolog; choroidermia; choroidermia (RAB escort protein 1); DXS540; GGTA; HSD-32; Rab escort protein 1; rab proteins geranylgeranyltransferase component A 1; REP1; REP-1; TCD; TCD protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1121
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P24386
• Gene Symbols: CHM
• Immunogen: Recombinant protein corresponding to Human CHM. Recombinant protein control fragment (Product #RP-92170).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG