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Invitrogen™ CHM Polyclonal Antibody
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Catalog No. PIPA579043
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100 μg
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Catalog No. Quantity
PIPA579043 100 μg
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Catalog No. PIPA579043 Supplier Invitrogen™ Supplier No. PA579043
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell, human A431 whole cell, human 293T whole cell, rat liver tissue, mouse liver tissue .

Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B composed of RABGGTA and RABGGTB, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CHM
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and 0.05mg sodium azide
Gene CHM
Gene Accession No. P24386, P37727, Q9QXG2
Gene Alias CHM; CHM, Rab escort protein 1; choroideraemia protein homolog; choroideremia (Rab escort protein 1); Choroideremia protein; Choroideremia protein homolog; choroidermia; choroidermia (RAB escort protein 1); DXS540; GGTA; HSD-32; Rab escort protein 1; rab proteins geranylgeranyltransferase component A 1; REP1; REP-1; TCD; TCD protein
Gene Symbols CHM
Host Species Rabbit
Immunogen E. coli-derived human CHM recombinant protein (Position: A193-Q380).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1121, 12662, 24942
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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