Invitrogen™ CHM Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5109530

Catalog No. PIPA5109530

Description

Immunogen sequence: KNHALVTSAN STEAADSAFL PTEDESLSTM SCEMLTEQTP SSDPENALEV NGAEVTGEKE NHCDDKTCVP STSAEDMSEN VPIAEDTTEQ P.

Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B composed of RABGGTA and RABGGTB, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation.

Specifications

• Antigen: CHM
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CHM
• Gene Alias: CHM; CHM, Rab escort protein 1; choroideraemia protein homolog; choroideremia (Rab escort protein 1); Choroideremia protein; Choroideremia protein homolog; choroidermia; choroidermia (RAB escort protein 1); DXS540; GGTA; HSD-32; Rab escort protein 1; rab proteins geranylgeranyltransferase component A 1; REP1; REP-1; TCD; TCD protein
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1121
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.07 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P24386
• Gene Symbols: CHM
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-210 of human CHM (NP_000381.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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