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Invitrogen™ CHM Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5109530
Description
Immunogen sequence: KNHALVTSAN STEAADSAFL PTEDESLSTM SCEMLTEQTP SSDPENALEV NGAEVTGEKE NHCDDKTCVP STSAEDMSEN VPIAEDTTEQ P.
Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B composed of RABGGTA and RABGGTB, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation.
Specifications
CHM | |
Polyclonal | |
Unconjugated | |
CHM | |
CHM; CHM, Rab escort protein 1; choroideraemia protein homolog; choroideremia (Rab escort protein 1); Choroideremia protein; Choroideremia protein homolog; choroidermia; choroidermia (RAB escort protein 1); DXS540; GGTA; HSD-32; Rab escort protein 1; rab proteins geranylgeranyltransferase component A 1; REP1; REP-1; TCD; TCD protein | |
Rabbit | |
Affinity Chromatography | |
RUO | |
1121 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Western Blot | |
1.07 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P24386 | |
CHM | |
Recombinant fusion protein containing a sequence corresponding to amino acids 120-210 of human CHM (NP_000381.1). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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