Invitrogen™ CHMP1B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA563997

Catalog No. PIPA563997

Description

Immunogen sequence: QNQVDMLLQE MADEAGLDLN MELPQGQTGS VGTSVASAEQ DELSQRLARL RDQV Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 96%.

CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 ).

Specifications

• Antigen: CHMP1B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CHMP1B
• Gene Alias: 2810405I11Rik; C10orf2; C18orf2; C18-ORF2; Charged multivesicular body protein 1b; charged multivesicular body protein 1b-1; CHMP1.5; CHMP1.5 protein; chmp1b; Chmp1b1; CHMP1b-1; chromatin modifying protein 1B; chromatin-modifying protein 1b; Chromatin-modifying protein 1b-1; fb10c03; hVps46-2; hypothetical protein LOC336426; Similar to RIKEN cDNA 2810405I11 gene; vacuolar protein sorting 46-2; vacuolar protein sorting-associated protein 46-2; Vps46-2; Vps46B; wu:fb10c03; zgc:56134
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57132
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q7LBR1
• Gene Symbols: CHMP1B
• Immunogen: Recombinant protein corresponding to Human CHMP1B. Recombinant protein control fragment (Product #RP-103426).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov