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Invitrogen™ CHMP2A Polyclonal Antibody
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Catalog No. PIPA587855
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100 μL
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PIPA587855 100 μL
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Catalog No. PIPA587855 Supplier Invitrogen™ Supplier No. PA587855
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MDLLFGRRKT PEELLRQNQR ALNRAMRELD RERQKLETQE KKIIADIKKM AKQGQMDAVR IMAKDLVRTR RYVRKFVLMR ANIQAVSLKI QTLKSNNSMA QAMKGVTKAM GTMNRQLKLP QIQKIMMEFE RQAEIMDMKE EMMNDAIDDA MGDEEDEEES DAVVSQVLDE LGLSLTDELS NLPSTGGSLS VAAGGKKAEA AASALADADA DLEERLKNLR RD; Positive Samples: A-431, HepG2, SW480; Cellular Location: Cytoplasmic side, Late endosome membrane, Peripheral membrane protein.

CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A is required for both MVB formation and regulation of cell cycle progression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CHMP2A
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.26 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CHMP2A
Gene Accession No. O43633
Gene Alias 1500016L11Rik; BC2; BC-2; Charged multivesicular body protein 2a; CHMP2; CHMP2A; chromatin modifying protein 2A; chromatin-modifying protein 2a; fj10d05; hypothetical protein LOC523847; mVps2; putative breast adenocarcinoma marker; putative breast adenocarcinoma marker (32kD); putative breast adenocarcinoma marker BC-2; RGD1305050; Vacuolar protein sorting-associated protein 2; vacuolar protein sorting-associated protein 2-1; vacuolar protein-sorting-associated protein 2; VPS2; VPS2 homolog A; vps2-1; VPS2A; wu:fi18h03; wu:fj10d05; zgc:55361
Gene Symbols CHMP2A
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-222 of human CHMP2A (NP_0552681).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27243
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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