Invitrogen™ CHMP2B Monoclonal Antibody (2H6-1E6)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA521591

Catalog No. PIMA521591

Description

Peptide Sequence: MASLFKKKTV DDVIKEQNRE LRGTQRAIIR DRAALEKQEK QLELEIKKMA KIGNKEACKV LAKQLVHLRK QKTRTFAVSS KVTSMSTQTK VMNSQMKMAG AMSTTAKTMQ AVNKKMDPQK TLQTMQNFQK ENMKMEMTEE MINDTLDDIF DGSDDEEESQ DIVNQVLDEI GIEISGKMAK APSAARSLPS ASTSKATISD EEIERQLKAL GVD.

CHMP2B, also known as CHMP2.5 or vacuolar protein-sorting-associated protein 2-2, is a 213 amino acid cytosolic protein. Widely expressed in brain, heart, skeletal muscle, small intestine, pancreas, lung, placenta and leukocytes, CHMP2B associates directly with CHMP2A and vps4 for the disassembly of the ESCRT-III complex. Defects in the gene encoding CHMP2B have been shown to cause chromosome 3-linked frontotemporal dementia (FTD3).

Specifications

• Antigen: CHMP2B
• Classification: Monoclonal
• Concentration: 0.27 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q9UQN3
• Gene Symbols: Chmp2b
• Immunogen: CHMP2B (AAH01553.1, 1 a.a. ~ 213 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: ELISA
• Clone: 2H6-1E6
• Conjugate: Unconjugated
• Gene: Chmp2b
• Gene Alias: 1190006E07Rik; ALS17; CGI-84; Charged multivesicular body protein 2b; charged multivesicular body protein 2Bb; CHMP family; CHMP2.5; CHMP2B; chmp2bb; chmp2bl; chromatin modifying protein 2B; chromatin modifying protein 2B, like; chromatin modifying protein 2Bb; chromatin-modifying protein 2b; DMT1; hVps2-2; hypothetical protein LOC615954; hypothetical protein zgc:77025; RGD1306781; si:ch211-106g5.3; Vacuolar protein sorting-associated protein 2-2; vacuolar protein-sorting-associated protein 2-2; VPS2 homolog B; VPS2-2; VPS2B; zgc:77025
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 25978
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid