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Invitrogen™ CHMP2B Polyclonal Antibody
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Catalog No. PIPA592444
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100 μL
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PIPA592444 100 μL
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Catalog No. PIPA592444 Supplier Invitrogen™ Supplier No. PA592444
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MASLFKKKTV DDVIKEQNRE LRGTQRAIIR DRAALEKQEK QLELEIKKMA KIGNKEACKV LAKQLVHLRK QKTRTFAVSS KVTSMSTQTK VMNSQMKMAG AMSTTAKTMQ AVNKKMDPQK TLQTMQNFQK ENMKMEMTEE MINDTLDDIF DGSDDEEESQ DIVNQVLDEI GIEISGKMAK APSAARSLPS ASTSKATISD EEIERQLKAL GVD; Positive Samples: MCF7, BT-474, 22Rv1, Lovo, A-549, Mouse lung, Mouse testis, Mouse kidney; Cellular Location: Cytoplasm, Late endosome membrane, Peripheral membrane protein, cytosol.

CHMP2B, also known as CHMP2.5 or vacuolar protein-sorting-associated protein 2-2, is a 213 amino acid cytosolic protein. Widely expressed in brain, heart, skeletal muscle, small intestine, pancreas, lung, placenta and leukocytes, CHMP2B associates directly with CHMP2A and vps4 for the disassembly of the ESCRT-III complex. Defects in the gene encoding CHMP2B have been shown to cause chromosome 3-linked frontotemporal dementia (FTD3).
TRUSTED_SUSTAINABILITY

Specifications

Antigen CHMP2B
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.22 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Chmp2b
Gene Accession No. Q8BJF9, Q9UQN3
Gene Alias 1190006E07Rik; ALS17; CGI-84; Charged multivesicular body protein 2b; charged multivesicular body protein 2Bb; CHMP family; CHMP2.5; CHMP2B; chmp2bb; chmp2bl; chromatin modifying protein 2B; chromatin modifying protein 2B, like; chromatin modifying protein 2Bb; chromatin-modifying protein 2b; DMT1; hVps2-2; hypothetical protein LOC615954; hypothetical protein zgc:77025; RGD1306781; si:ch211-106g5.3; Vacuolar protein sorting-associated protein 2-2; vacuolar protein-sorting-associated protein 2-2; VPS2 homolog B; VPS2-2; VPS2B; zgc:77025
Gene Symbols Chmp2b
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-213 of human CHMP2B (NP_0547622).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25978, 68942
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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