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Invitrogen™ CHMP4B Polyclonal Antibody
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Catalog No. PIPA559552
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100 μL
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PIPA559552 100 μL
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Catalog No. PIPA559552 Supplier Invitrogen™ Supplier No. PA559552
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SVFGKLFGAG GGKAGKGGPT PQEAIQRLRD TEEMLSKK Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

CHMP4B is a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CHMP4B
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.8 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CHMP4B
Gene Accession No. Q9H444
Gene Alias 2010012F05Rik; C20orf178; C76846; charged multivesicular body protein 4b; CHMP4A; CHMP4B; chromatin modifying protein 4B; chromatin-modifying protein 4b; CTPP3; CTRCT31; dJ553F4.4; hSnf7-2; hVps32-2; RGD1309846; RGD1565889; Shax1; SNF7; SNF7 homolog associated with Alix 1; Snf7 homologue associated with Alix 1; Snf7-2; Vacuolar protein sorting-associated protein 32-2; vacuolar protein-sorting-associated protein 32-2; Vps32-2; VPS32B
Gene Symbols CHMP4B
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CHMP4B. Recombinant protein control fragment (Product #RP-99355).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 128866
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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