Invitrogen™ CHMP5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521787

Catalog No. PIPA521787

Description

Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji, mouse stomach. Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (92%), Pig (100%), Chicken (94%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein family. These proteins are components of ESCRT-III, a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies. Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression.

Specifications

• Antigen: CHMP5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CHMP5
• Gene Alias: 2210412K09Rik; apoptosis-related protein PNAS-2; AW545668; C9orf83; CGI-34; Charged multivesicular body protein 5; CHMP5; chromatin modifying protein 5; chromatin-modifying protein 5; HGNC:26942; HSPC177; hVps60; likely ortholog of H. sapiens SNF7 domain containing 2; PNAS-114; PNAS-2; SNF7 domain containing 2; SNF7 domain-containing protein 2; SNF7DC2; Vacuolar protein sorting-associated protein 60; Vps60
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51510, 76959
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9D7S9, Q9NZZ3
• Gene Symbols: CHMP5
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 202 of CHMP5 (Uniprot ID#Q9NZZ3).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG