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Invitrogen™ Cholera Toxin beta Polyclonal Antibody, HRP
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Catalog No. PA173189
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1 mL
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PA173189 1 mL
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Catalog No. PA173189 Supplier Invitrogen™ Supplier No. PA173189
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Description

Rabbit Polyclonal Antibody

The PA1-73189 antibody reacts with Cholera toxin beta subunit. PA1-73189 has been successfully used in ELISA applications. The PA1-73189 antibody was raised against purified Choleragenoid.

Cholera toxin (sometimes abbreviated to CTX, Ctx, or CT) is a protein complex secreted by the bacterium Vibrio cholerae. CTX is the causative agent of cholera infection. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP. The beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cholera Toxin beta
Applications ELISA
Classification Polyclonal
Concentration 1.0 mg/mL
Conjugate HRP
Formulation PBS with 10mg/mL BSA and 0.002% thimerosal; pH 7.2
Gene Alias CTB; CTX; VC1456
Host Species Rabbit
Immunogen Purified Choleragenoid.
Purification Method Protein A
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Bacteria
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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