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Invitrogen™ CHOP Polyclonal Antibody
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Catalog No. PIPA5119664
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100 μL
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PIPA5119664 100 μL
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Catalog No. PIPA5119664 Supplier Invitrogen™ Supplier No. PA5119664
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Description

Rabbit Polyclonal Antibody

Positive Control: Mouse brain tissue lysate, LOVO, mouse testis tissue lysate. Subcellular Location: Nucleus.

GADD153 is a small nuclear protein that is capable of dimerizing with transcription factors C/EBP alpha and beta. Once dimerized, this complex inhibits the normal binding and function of C/EBP to classical binding sites. Inversely, the C/EBP GADD153 dimer gains binding activity to other non classical C/EBP stress related targets. Under normal cellular conditions this protein is not expressed in detectable levels, but is highly unregulated during times of cellular/ER stress. Examples of GADD153 inducing stress include: treatment with tunicamycin, nutrient starvation and reducing agents that interfere with the calcium flux across the ER membrane.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CHOP
Applications Flow Cytometry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene DDIT3
Gene Accession No. P35638, P35639
Gene Alias C/EBP homologous protein; C/EBP homoologous protein 10; C/EBP zeta; C/EBP-homologous protein; C/EBP-homologous protein 10; CCAAT/enhancer-binding protein homologous protein; CEBPZ; CHOP; CHOP10; CHOP-10; Ddit3; DDIT-3; ddit3.L; DNA damage inducible transcript 3; DNA damage inducible transcript 3 L homeolog; DNA damage-inducible transcript 3 protein; DNA-damage inducible transcript 3; DNA-damage-inducible transcript 3; GADD153; growth arrest and DNA damage-inducible; growth arrest and DNA damage-inducible protein GADD153; Growth arrest and DNA-damage-inducible protein GADD153; MGC4154; transcription factor GADD153; Xchop; XELAEV_18013440mg
Gene Symbols DDIT3
Host Species Rabbit
Immunogen Synthetic peptide within human DDIT3 aa 60-130.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13198, 1649
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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