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Tocris Bioscience™ CHR 6494 trifluoroacetate
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Catalog No. 532610
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10 mg
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Catalog No. Quantity
53-261-0 10 mg
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Catalog No. 53-261-0 Supplier Tocris Bioscience™ Supplier No. 5326/10
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Description

Potent and selective haspin inhibitor

CHR 6494 trifluoroacetate is a potent and selective haspin kinase inhibitor (IC50 = 2 nM). Selective over 27 other protein kinases including Aurora B kinase. Induces cell cycle arrest at G2/M, inhibits cell proliferation and promotes apoptosis in multiple cancer cell lines. Inhibits angiogenesis ex vivo and attenuates tumor growth of HCT-116 xenografts in rats.

Specifications

Quantity 10 mg
Product Type CHR 6494 trifluoroacetate
Purity >98%
Molecular Weight (g/mol) 406.36
Inhibitors CHR 6494 trifluoroacetate

For Research Use Only

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