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Invitrogen™ CHRDL2 Monoclonal Antibody (328905)
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Catalog No. PIMA524056
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100 μg
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PIMA524056 100 μg
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Catalog No. PIMA524056 Supplier Invitrogen™ Supplier No. MA524056
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Rat Monoclonal Antibody

In direct ELISAs and Western blots, no cross-reactivity with recombinant human CHRDL2, recombinant mouse (rm) CHRDL1, or rmChordin is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

CHRDL2 encodes a member of the chordin family of proteins. Chordin family members are secreted proteins that share a cysteine-rich pro-collagen repeat domain and associate with members of the transforming growth factor beta superfamily. In vitro assays demonstrate a direct interaction between the encoded protein and human activin A. This gene is expressed in many tissues including osteoblasts, where it is differentially expressed during differentiation. In addition, its expression is upregulated in human osteoarthritic joint cartilage, suggesting a role in adult cartilage regeneration.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CHRDL2
Applications Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 328905
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene Chrdl2
Gene Accession No. Q8VEA6
Gene Alias 1810022C01Rik; BNF1; BNF-1; Breast tumor novel factor 1; CHL2; chordin like 2; chordin-like 2; chordin-like protein 2; Chordin-related protein 2; CHRDL2; FKSG37; UNQ765/PRO1557
Gene Symbols Chrdl2
Host Species Rat
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse Chordin-like 2/CHRDL2 Gln24-Leu426.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 69121
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG2a
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