Invitrogen™ CHRDL2 Monoclonal Antibody (328905)

Rat Monoclonal Antibody

Supplier:  Invitrogen™ MA524056

Catalog No. PIMA524056

Description

In direct ELISAs and Western blots, no cross-reactivity with recombinant human CHRDL2, recombinant mouse (rm) CHRDL1, or rmChordin is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

CHRDL2 encodes a member of the chordin family of proteins. Chordin family members are secreted proteins that share a cysteine-rich pro-collagen repeat domain and associate with members of the transforming growth factor beta superfamily. In vitro assays demonstrate a direct interaction between the encoded protein and human activin A. This gene is expressed in many tissues including osteoblasts, where it is differentially expressed during differentiation. In addition, its expression is upregulated in human osteoarthritic joint cartilage, suggesting a role in adult cartilage regeneration.

Specifications

• Antigen: CHRDL2
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q8VEA6
• Gene Symbols: Chrdl2
• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Chordin-like 2/CHRDL2 Gln24-Leu426.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
• Clone: 328905
• Conjugate: Unconjugated
• Gene: Chrdl2
• Gene Alias: 1810022C01Rik; BNF1; BNF-1; Breast tumor novel factor 1; CHL2; chordin like 2; chordin-like 2; chordin-like protein 2; Chordin-related protein 2; CHRDL2; FKSG37; UNQ765/PRO1557
• Host Species: Rat
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 69121
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized