Invitrogen™ CHRM1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588481

Catalog No. PIPA588481

Description

Immunogen sequence: WELGYWLCYV NSTINPMCYA LCNKAFRDTF RLLLLCRWDK RRWRKIPKRP GSVHRTPSRQ C; Positive Samples: U-87MG, HepG2; Cellular Location: Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse.

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.

Specifications

• Antigen: CHRM1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CHRM1
• Gene Alias: acetylcholine receptor; acetylcholine receptor, muscarinic 1; AChR M1; cholinergic receptor; cholinergic receptor muscarinic 1; Cholinergic receptor, muscarin 1; cholinergic receptor, muscarinic 1; cholinergic receptor, muscarinic 1, CNS; CHRM1; Chrm-1; HM1; M1; M1 mAChR; m1 muscarinic acetylcholine receptor protein; M1R; MGC30125; muscarinic acetylcholine receptor M1; muscarinic receptor M1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1128, 12669, 25229
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.33 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P08482, P11229, P12657
• Gene Symbols: CHRM1
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 400-460 of human CHRM1 (NP_0007292).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG