Invitrogen™ CHRM1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA590876

Catalog No. PIPA590876

Description

Positive Samples: U-87MG, HepG2; Cellular Location: Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse Immunogen sequence: SPETPPGRCC RCCRAPRLLQ AYSWKEEEEE DEGSMESLTS SEGEEPGSEV VIKMPMVDPE AQAPTKQPPR SSPNTVKRPT KKGRDRAGKG QKPRGKEQLA.

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.

Specifications

• Antigen: CHRM1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CHRM1
• Gene Alias: acetylcholine receptor; acetylcholine receptor, muscarinic 1; AChR M1; cholinergic receptor; cholinergic receptor muscarinic 1; Cholinergic receptor, muscarin 1; cholinergic receptor, muscarinic 1; cholinergic receptor, muscarinic 1, CNS; CHRM1; Chrm-1; HM1; M1; M1 mAChR; m1 muscarinic acetylcholine receptor protein; M1R; MGC30125; muscarinic acetylcholine receptor M1; muscarinic receptor M1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1128, 12669, 25229
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 2.67 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: P08482, P11229, P12657
• Gene Symbols: CHRM1
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 251-350 of human CHRM1 (NP_0007292).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG