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Invitrogen™ CHRM2 Polyclonal Antibody
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Catalog No. PIPA5142925
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100 μg
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PIPA5142925 100 μg
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Catalog No. PIPA5142925 Supplier Invitrogen™ Supplier No. PA5142925
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Goat Polyclonal Antibody

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.

Muscarinic cholinergic receptor 2 (CHRM2) is an Acetylcholine Receptor has been suggested to function as a presynaptic autoreceptor that inhibits acetylcholine release. The M2 receptor has also been suggested to mediate smooth muscle contractility. Alzheimer's disease (AD) involves selective loss of M2 subtype receptors in cortical and hippocampal regions of the human brain. Increase in M2 receptor heterozygosity has been associated with depression in women. The M2 receptor has been reported to be expressed in various regions of the brain including the cerebellum, cerebral cortex, hippocampus, medulla, striatum, and thalamus, and in lung and prostate.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CHRM2
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene CHRM2
Gene Accession No. Q9ERZ4
Gene Alias 7TM receptor; acetylcholine receptor; acetylcholine receptor, muscarinic 2; AChR M2; AChR-M2; Acm2; cardiac muscarinic acetylcholine receptor; cholinergic receptor; cholinergic receptor muscarinic 2; cholinergic receptor, muscarinic 2; cholinergic receptor, muscarinic 2, cardiac; cholinergic receptor, muscarinic 2, isoform a; Chrm2; Chrm-2; FLJ43243; HM2; M2; M2 muscarinic acetylcholine receptor; m2AChR; M2-mAChR; MGC120006; MGC120007; muscarinic acetylcholine receptor 2; muscarinic acetylcholine receptor m2; muscarinic M2 receptor; muscarinic receptor m2; unnamed protein product
Gene Symbols CHRM2
Host Species Goat
Immunogen Peptide with sequence C-QNGDEKQNIVARK (aa 352-364).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 243764
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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