Invitrogen™ CHRNA10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101716

Catalog No. PIPA5101716

Description

Antibody detects endogenous levels of total CHRNA10.

Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.

Specifications

• Antigen: CHRNA10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CHRNA10
• Gene Alias: acetylcholine receptor; acetylcholine receptor, nicotinic, alpha 10 (neuronal); cholinergic receptor; cholinergic receptor nicotinic alpha 10 subunit; cholinergic receptor, nicotinic alpha 10; cholinergic receptor, nicotinic, alpha 10 (neuronal); cholinergic receptor, nicotinic, alpha polypeptide 10; Chrna10; NACHR alpha 10; NACHR alpha-10; NACHRA10; Neuronal acetylcholine receptor subunit alpha-10; neuronal nicotinic acetylcholine receptor subunit; nicotinic acetylcholine receptor subunit alpha 10; nicotinic acetylcholine receptor subunit alpha-10
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 504186, 57053, 64574
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9GZZ6, Q9JLB5
• Gene Symbols: CHRNA10
• Immunogen: A synthesized peptide derived from human CHRNA10(Accession Q9GZZ6), corresponding to amino acid residues A394-L444.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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