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Invitrogen™ CHRNA3 Polyclonal Antibody
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Catalog No. PIPA5116458
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PIPA5116458 100 μL
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Catalog No. PIPA5116458 Supplier Invitrogen™ Supplier No. PA5116458
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Description

Rabbit Polyclonal Antibody

Positive controls: SH-SY5Y cell lysate, Hela cell lysate, human stomach tissue lysate, rat brain tissue lysate, rat testis tissue, human liver carcinoma tissue, human colon carcinoma tissue, human skin tissue, human breast carcinoma tissue, human kidney tissue, human esophagus tissue, human small intestine tissue, human tonsil carcinoma tissue, SH-SY5Y.

CHRNA3 locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CHRNA3
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.2% BSA and 0.05% sodium azide; pH 7.4
Gene CHRNA3
Gene Accession No. P04757, P32297, Q8R4G9
Gene Alias (a)3; A730007P14Rik; acetylcholine receptor; Acetylcholine receptor alpha 3 (neuronal nicotine); Acra3; Acra-3; alpha 3; cetylcholine receptor alpha 3 (neuronal nicotine); cholinergic receptor; cholinergic receptor nicotinic alpha 3 subunit; cholinergic receptor nicotinic alpha polypeptide 4; cholinergic receptor, nicotinic alpha 3; cholinergic receptor, nicotinic, alpha 3 (neuronal); cholinergic receptor, nicotinic, alpha polypeptide 3; CHRNA3; LNCR2; nAChR alpha 3; NACHRA3; Neuronal acetylcholine receptor subunit alpha-3; neuronal nicotinic acetylcholine receptor, alpha 3 subunit; neuronal nicotinic acetylcholine receptor, alpha3 subunit; PAOD2
Gene Symbols CHRNA3
Host Species Rabbit
Immunogen Synthetic peptide within rat CHRNA3 aa 73-122.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 110834, 1136, 25101
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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