CHRNA4 Mouse anti-Human, Clone:7B4H1, Abnova™

Catalog No.	Quantity
89-334-005	100 μg

Catalog No. 89-334-005 Supplier Abnova Corporation Supplier No. MAB17539

Description

Mouse monoclonal antibody raised against recombinant human CHRNA4.

This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. [provided by RefSeq]

Specifications

• Antigen: CHRNA4
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 7B4H1
• Conjugate: Unconjugated
• Description: cholinergic receptor, nicotinic, alpha 4
• Dilution: ELISA (1:10000)
  Western Blot (1:500-1:2000)
  Immunocytochemistry
  Flow Cytometry
  Immunohistochemistry
  The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.05% sodium azide)
• Gene: CHRNA4
• Gene Alias: BFNC, EBN, EBN1, FLJ95812, NACHR, NACHRA4, NACRA4
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to amino acid 29-242 of human CHRNA4 from E. coli.
• Quantity: 100 μg
• Gene ID (Entrez): 1137
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1