CHRNB1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA552213

Catalog No. PIPA552213

Description

Immunogen sequence: LSVVVLNLHH RSPHTHQMPL WVRQIFIHKL PLYLRLKRPK PERDLMPEPP HCSSPGSGWG RGTDEYFIRK PPSDFLFPKP NRFQPELSAP DLRRFIDGPN RAVALLPELR EVVSSISYIA RQLQEQEDHD ALKEDWQF Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 86%.

The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.

Specifications

• Antigen: CHRNB1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CHRNB1
• Gene Alias: CHRNB1; ACHRB; cholinergic receptor, nicotinic, beta 1 (muscle) ; CHRNB; CMS1D; CMS2A; SCCMS; cholinergic receptor, nicotinic, beta polypeptide 1 (muscle); nicotinic acetylcholine receptor beta 1 subunit
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1140
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P11230
• Gene Symbols: CHRNB1
• Immunogen: Recombit protein corresponding to Human CHRNB1
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Research Use Only