Invitrogen™ CHRNB2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597249

Catalog No. PIPA597249

Description

Immunogen sequence: LEKLPALLFM QQPRHHCARQ RLRLRRRQRE REGAGALFFR EAPGADSCTC FVNRASVQGL AGAFGAEPAP VAGPGRSGEP CGCGLREAVD G; Positive Samples: HepG2, SH-SY5Y, Mouse liver, Rat liver; Cellular Location: Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse.

Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy.

Specifications

• Antigen: CHRNB2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CHRNB2
• Gene Alias: [b]2-nAchR; acetylcholine receptor; acetylcholine receptor beta 2 neural; acetylcholine receptor, nicotinic, beta 2 (neuronal); Acrb2; Acrb-2; beta2 human neuronal nicotinic acetylcholine receptor; C030030P04Rik; cholinergic receptor; cholinergic receptor nicotinic beta 2 subunit; cholinergic receptor nicotinic beta polypeptide 2; cholinergic receptor, nicotinic beta 2; cholinergic receptor, nicotinic, beta 2 (neuronal); cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal); cholinergic receptor, nicotinic, beta subunit 2; CHRNB2; EFNL3; nAChRB2; N-alpha 1; Neuronal acetylcholine receptor non-alpha-1 chain; neuronal acetylcholine receptor subunit beta-2; neuronal acetylcholine receptor, beta 2; neuronal nicotinic acetylcholine receptor; neuronal nicotinic acetylcholine receptor beta 2; nicotinic acetylcholine receptor beta 2 subunit
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1141, 11444, 54239
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 0.76 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P12390, P17787, Q9ERK7
• Gene Symbols: CHRNB2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 340-430 of human CHRNB2 (NP_0007391).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG