Invitrogen™ CHRNB2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5119689

Catalog No. PIPA5119689

Description

Positive Control: Jurkat cell lysates, A549, SH-SY5Y, rat spinal cord tissue, mouse brain tissue. Subcellular Location: Postsynaptic cell membrane, cell membrane.

Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy.

Specifications

• Antigen: CHRNB2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CHRNB2
• Gene Alias: [b]2-nAchR; acetylcholine receptor; acetylcholine receptor beta 2 neural; acetylcholine receptor, nicotinic, beta 2 (neuronal); Acrb2; Acrb-2; beta2 human neuronal nicotinic acetylcholine receptor; C030030P04Rik; cholinergic receptor; cholinergic receptor nicotinic beta 2 subunit; cholinergic receptor nicotinic beta polypeptide 2; cholinergic receptor, nicotinic beta 2; cholinergic receptor, nicotinic, beta 2 (neuronal); cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal); cholinergic receptor, nicotinic, beta subunit 2; CHRNB2; EFNL3; nAChRB2; N-alpha 1; Neuronal acetylcholine receptor non-alpha-1 chain; neuronal acetylcholine receptor subunit beta-2; neuronal acetylcholine receptor, beta 2; neuronal nicotinic acetylcholine receptor; neuronal nicotinic acetylcholine receptor beta 2; nicotinic acetylcholine receptor beta 2 subunit
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1141, 11444, 54239
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P12390, P17787, Q9ERK7
• Gene Symbols: CHRNB2
• Immunogen: Synthetic peptide within rat CHRNB2 aa 50-150.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG