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Invitrogen™ CHRNG Polyclonal Antibody
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Catalog No. PIPA5103556
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PIPA5103556 100 μL
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Catalog No. PIPA5103556 Supplier Invitrogen™ Supplier No. PA5103556
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CHRNG.

The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third week of gestation in humans. The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes. Mutations in this gene cause Escobar syndrome and a lethal form of multiple pterygium syndrome. Muscle-type acetylcholine receptor is the major antigen in the autoimmune disease myasthenia gravis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CHRNG
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CHRNG
Gene Accession No. P04760, P07510, P18916
Gene Alias acetylcholine receptor; Acetylcholine receptor subunit gamma; acetylcholine receptor, muscle, gamma subunit; acetylcholine receptor, nicotinic, gamma (muscle); AChR gamma subunit; Achr-3; ACHRG; Acrg; cholinergic receptor; cholinergic receptor nicotinic gamma subunit; cholinergic receptor, nicotinic gamma; cholinergic receptor, nicotinic, gamma (muscle); cholinergic receptor, nicotinic, gamma polypeptide; Chrng; chrng variant N1; chrng variant N2; nicotinic acetylcholine receptor gamma subunit
Gene Symbols CHRNG
Host Species Rabbit
Immunogen A synthesized peptide derived from human CHRNG(Accession P07510), corresponding to amino acid residues A20-E70.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11449, 1146, 25753
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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