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Chromogranin A Antibody (CGA/413 + CHGA/777 + CHGA/798), DyLight 650, Novus Biologicals™
SDP

Catalog No. NB007445 Shop All R&D Systems Products
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NB007445 0.1 mL
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Catalog No. NB007445 Supplier Novus Biologicals Supplier No. NBP247846C
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Description

Mouse Monoclonal Antibody

Chromogranin A Monoclonal specifically detects Chromogranin A in Human, Mouse, Rat, Porcine, Monkey samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen Chromogranin A
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone CGA/413 + CHGA/777 + CHGA/798
Conjugate DyLight 650
Dilution Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias betagranin (N-terminal fragment of chromogranin A), CGA, chromogranin A (parathyroid secretory protein 1), chromogranin-A, parathyroid secretory protein 1, Pituitary secretory protein I, SP-I
Gene Symbols CHGA
Host Species Mouse
Immunogen Recombinant human Chromogranin A protein (Uniprot: P10645)
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Apoptosis, Cancer, Neuronal Cell Markers, Tumor Biomarkers
Primary or Secondary Primary
Test Specificity Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Target Species Human, Mouse, Rat, Pig, Monkey
Content And Storage Store at 4°C in the dark.
Isotype IgG2b κ
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