Chromogranin A Monoclonal Antibody (PHE5), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA513281

Catalog No. PIMA513281

Description

MA5-13281 targets Chromogranin A in IF and IHC (P) applications and shows reactivity with Human and Non-human primate samples. The MA5-13281 immunogen is human pheochromocytoma.

Chromogranin A (CHGA) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocine cells. CHGA is a precursor to three biologically active peptides: vasostatin, pancreastatin, and parastatin. These peptides act as autocine or paracrine negative modulators of the neuroendocrine system. CHGA is an excellent marker for carcinoid tumors, pheo-chromocytomas, paragangliomas, and other neuro-endocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.

Specifications

• Antigen: Chromogranin A
• Classification: Monoclonal
• Concentration: 0.2 mg/mL
• Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
• Gene Accession No.: P10645
• Gene Symbols: Chga
• Immunogen: Human pheochromocytoma
• Quantity: 500 μL
• Primary or Secondary: Primary
• Target Species: Human, Non-human Primate
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin)
• Clone: PHE5
• Conjugate: Unconjugated
• Gene: Chga
• Gene Alias: AL-11; AL26; Beta-granin; betagranin (N-terminal fragment of chromogranin A); catestatin; CgA; CHGA; ChrA; chromofungin; chromogranin A; chromogranin A (parathyroid secretory protein 1); chromogranin A precursor; chromogranin-A; CTNNB; DKFZp686D02253; EA-92; ER-37; ES-43; FLJ25606; FLJ37923; GE-25; GR-44; GV-19; LF-19; LOW QUALITY PROTEIN: chromogranin-A; MGC105435; Pancreastatin; Parastatin; parathyroid secretory protein 1; p-Glu serpinin precursor; pituitary secretory protein I; Serpinin; Serpinin-RRG; SL21; SP-I; SS-18; Vasostatin I; Vasostatin II; Vasostatin-1; Vasostatin-2; WA-8; WE-14
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 1113
• Content And Storage: 4° C
• Form: Liquid