CHST1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 125041AP150UL

Catalog No. 50-172-8029

Description

Carbohydrate sulfotransferase 1 (CHST1), also referred to as KSGal6ST or KSST, is a keratan sulfate sulfotransferase. It is predomitly expressed in brain and skeletal muscle and localizes to the trans-Golgi network. CHST1 is responsible for mediating the sulfation of keratan in the cornea, which is important in maintaining corneal transparency. In particular, CHST1 catalyzes the transfer of sulfate groups from 3′-phosphoadenosine 5′-phosphosulfate to position six of internal or terminal galactose residues (preferentially the residues adjacent to sulfated GlcNAc) on growing keratan sulfate chains. CHST1 also contributes to the generation of L-selectin ligands. Mutations in the CHST1 gene may play a role in macular corneal dystrophy (MCD).

Specifications

• Antigen: CHST1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CHST1
• Gene Alias: C6ST, CHST1, GST 1, KS6ST, KSGal6ST, KSST
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 295934, 76969, 8534
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.32 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: O43916, Q5RJQ0, Q9EQC0
• Gene Symbols: CHST1
• Immunogen: CHST1 Fusion Protein Ag3183
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG