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Invitrogen™ CHST14 Polyclonal Antibody
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Catalog No. PIPA5103702
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100 μL
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PIPA5103702 100 μL
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Catalog No. PIPA5103702 Supplier Invitrogen™ Supplier No. PA5103702
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CHST14.

Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sulfate. Plays a pivotal role in the formation of 4-0-sulfated IdoA blocks in dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA. GlcUA to IdoUA. Appears to have an important role in the formation of the cerbellar neural network during postnatal brain development.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CHST14
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CHST14
Gene Accession No. Q80V53, Q8NCH0
Gene Alias 2600016L03Rik; ATCS; carbohydrate (dermatan 4) sulfotransferase 14; carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14; carbohydrate sulfotransferase 14; CHST14; D4ST1; D4ST-1; dermatan 4 sulfotransferase 1; dermatan 4-sulfotransferase 1; dermatan-4-sulfotransferase-1; EDSMC1; hD4ST1; HNK1ST; UNQ1925/PRO4400
Gene Symbols CHST14
Host Species Rabbit
Immunogen A synthesized peptide derived from human CHST14(Accession Q8NCH0), corresponding to amino acid residues R246-V296.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 113189, 691394, 72136
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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