CHST14 Rabbit anti-Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA548649

Catalog No. PA548649

Description

Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sulfate. Plays a pivotal role in the formation of 4-0-sulfated IdoA blocks in dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA. GlcUA to IdoUA. Appears to have an important role in the formation of the cerbellar neural network during postnatal brain development.

Specifications

• Antigen: CHST14
• Classification: Polyclonal
• Formulation: PBS with 0.09% sodium azide
• Gene Accession No.: Q80V53
• Gene Symbols: CHST14
• Immunogen: KLH conjugated synthetic peptide between 178-205 amino acids from the Central region of human CHST14.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: Chst14
• Gene Alias: Carbohydrate sulfotransferase 14, Dermatan 4-sulfotransferase 1, D4ST-1, hD4ST1, CHST14, D4ST1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 72136
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid