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CHST14 Rabbit anti-Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA548649

Catalog No. PA548649

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sulfate. Plays a pivotal role in the formation of 4-0-sulfated IdoA blocks in dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA. GlcUA to IdoUA. Appears to have an important role in the formation of the cerbellar neural network during postnatal brain development.
Specifications

Specifications

CHST14
Polyclonal
PBS with 0.09% sodium azide
Q80V53
Carbohydrate sulfotransferase 14, Dermatan 4-sulfotransferase 1, D4ST-1, hD4ST1, CHST14, D4ST1
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
72136
Western Blot
Unconjugated
Chst14
Liquid
CHST14
KLH conjugated synthetic peptide between 178-205 amino acids from the Central region of human CHST14.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Mouse
Documents
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