Invitrogen™ CHST15 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597171

Catalog No. PIPA597171

Description

Immunogen sequence: LQVGLYAVYL LDWLSVFDKQ QFLILRLEDH ASNVKYTMHK VFQFLNLGPL SEKQEALMTK SPASNARRPE DRNLGPMWPI TQKILRDFYR PFNARLAQVL ADEAFAWKTT; Positive Samples: Raji, Rat heart; Cellular Location: Golgi apparatus membrane, Single-pass type II membrane protein.

GALNAC4S-6ST is a sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4, 6-SO(4)) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. GALNAC4S-6ST may also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression; however such results are unclear in vivo.

Specifications

• Antigen: CHST15
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CHST15
• Gene Alias: 4631426J05Rik; B cell RAG associated protein; B cell RAG associated protein (GALNAC4S-6ST); B-cell RAG-associated gene protein; Brag; carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15; carbohydrate sulfotransferase 15; Chst15; DKFZp781H1369; GalNAc 4-sulfate 6-O-sulfotransferase; GALNAC4S6ST; GALNAC4S-6ST; GalNAcS-6ST; hBRAG; KIAA0598; MAd5; MGC34346; mKIAA0598; N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase; RP11-47G11.1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 286974, 51363
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.77 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q7LFX5, Q8CHI9
• Gene Symbols: CHST15
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 452-561 of human CHST15 (NP_0569762).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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