Invitrogen™ CHST8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101487

Catalog No. PIPA5101487

Description

Antibody detects endogenous levels of total CHST8.

The protein encoded by this gene belongs to the sulfotransferase 2 family. It is predominantly expressed in the pituitary gland, and is localized to the Golgi membrane. This protein catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. It is responsible for sulfation of GalNAc on luteinizing hormone (LH), which is required for production of the sex hormones. Mice lacking this enzyme, exhibit increased levels of circulating LH, and precocious sexual maturation of both male and female mice. Alternatively spliced transcript variants have been found for this gene.

Specifications

• Antigen: CHST8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CHST8
• Gene Alias: 1500011J21Rik; AI426009; carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8; carbohydrate N-acetylgalactosamine 4-0 sulfotransferase 8; carbohydrate sulfotransferase 8; Chst8; GalNAc-4-O-sulfotransferase 1; GalNAc4ST; GALNAC4ST1; galNAc-4-ST1; galNAc4ST-1; N-acetylgalactosamine-4-O-sulfotransferase 1; PSS3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 308511, 64377, 68947
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q8BQ86, Q9H2A9
• Gene Symbols: CHST8
• Immunogen: A synthesized peptide derived from human CHST8(Accession Q9H2A9), corresponding to amino acid residues V345-L395.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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