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Tocris Bioscience™ CIA 1
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Catalog No. 749410
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Catalog No. Quantity
74-941-0 10 mg
74-945-0 50 mg
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Catalog No. 74-941-0 Supplier Tocris Bioscience™ Supplier No. 7494/10
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Description

COUP-TFII inhibitor

CIA 1 is an inhibitor of the nuclear receptor COUP-TFII (IC50 ranged from 1.2 μM to 7.6 μM, in prostate cancer cell lines). In vitro, CIA 1 inhibits growth of multiple prostate cancer cell lines and suppresses COUP-TFII activity to regulate its target genes. In vivo, CIA 1 reduces tumor growth in prostate cancer xenograft mouse models.

Specifications

Chemical Name or Material N-[2-(3,4-Dimethoxyphenyl)ethyl]-6-methylthieno[2,3-d]pyrimidin-4-amine hydrochloride
CAS 1049691-47-5
Quantity 10 mg
Target Additional Nuclear Receptor Compounds
Molecular Formula C17H19N3O2S.HCl
Purity 0.98
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