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Invitrogen™ cIAP2 Polyclonal Antibody

Catalog No. PIPA126473
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50 μg
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Catalog No. Quantity
PIPA126473 50 μg
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Catalog No. PIPA126473 Supplier Invitrogen™ Supplier No. PA126473

Description

Rabbit Polyclonal Antibody

PA1-26473 has been successfully used in Western blot procedures. By Western blot, this antibody detects a ~68 kDa band representing BIRC3 from Jurkat cell lysate.

The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen cIAP2
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.5% BSA, 30% glycerol and 0.01% Thimerosal; pH 7.2
Gene BIRC3
Gene Accession No. O08863, Q13489
Gene Alias AIP 2; AIP1; Api1; Api2; apoptosis inhibitor 1; apoptosis inhibitor 2; AW107670; baculoviral IAP repeat containing 3; baculoviral IAP repeat-containing 2; baculoviral IAP repeat-containing 3; baculoviral IAP repeat-containing protein 3; Birc2; Birc3; Cellular inhibitor of apoptosis 2; cIAP1; cIAP-1; cIAP2; C-IAP2; cIAP-2; H HIAP1; H MALT2; HAIP1; HIAP1; hIAP-1; HIAP2; IAP homolog; IAP homolog C; IAP1; IAP-1; IAP2; Inhibitor of apoptosis protein 1; MALT2; mammalian IAP homolog C; MIAP1; mIAP-1; MIAP2; MIHB; MIHC; RING finger protein 49; RING-type E3 ubiquitin transferase BIRC3; RNF49; TNFR2-TRAF signaling complex protein; TNFR2-TRAF-signaling complex protein 1
Gene Symbols BIRC3
Host Species Rabbit
Immunogen Synthetic peptide surrounding amino acid 510 of human cIAP-2.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11796, 330, 78971
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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