Invitrogen™ cIAP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA519514

Catalog No. PIPA519514

Description

For Western Blot, this antibody has non-specific bands at 150 kDa,35 kDa and 75 kDa. This antibody is predicted to react with mouse, rat, chicken and dog based on sequence homology.

The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified.

Specifications

• Antigen: cIAP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BIRC3
• Gene Alias: AIP 2; AIP1; Api1; Api2; apoptosis inhibitor 1; apoptosis inhibitor 2; AW107670; baculoviral IAP repeat containing 3; baculoviral IAP repeat-containing 2; baculoviral IAP repeat-containing 3; baculoviral IAP repeat-containing protein 3; Birc2; Birc3; Cellular inhibitor of apoptosis 2; cIAP1; cIAP-1; cIAP2; C-IAP2; cIAP-2; H HIAP1; H MALT2; HAIP1; HIAP1; hIAP-1; HIAP2; IAP homolog; IAP homolog C; IAP1; IAP-1; IAP2; Inhibitor of apoptosis protein 1; MALT2; mammalian IAP homolog C; MIAP1; mIAP-1; MIAP2; MIHB; MIHC; RING finger protein 49; RING-type E3 ubiquitin transferase BIRC3; RNF49; TNFR2-TRAF signaling complex protein; TNFR2-TRAF-signaling complex protein 1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 330, 78971
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 1% BSA and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q13489
• Gene Symbols: BIRC3
• Immunogen: Synthetic peptide conjugated to KLH derived from within residues 550 to the C-terminus of Human cIAP2.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG