Invitrogen™ CIB4 Polyclonal Antibody

Catalog No.	Quantity
PIPA5103673	100 μL

Catalog No. PIPA5103673 Supplier Invitrogen™ Supplier No. PA5103673

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CIB4.

CIB4 (calcium and integrin-binding family member 4) is a 185 amino acid protein that contains three EF-hand domains. CIB4 is closely related to CIB (CIB has one less EF-hand domain), which is known to bind to Integrin alpha II beta in platelets and is involved in signal transduction. The gene encoding CIB4 maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorders itosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alstrom syndrome, is caused by mutationsin the ALMS1 gene, which maps to chromosome 2.

Specifications

• Antigen: CIB4
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: Cib4
• Gene Accession No.: A0PJX0
• Gene Alias: 1700041E20Rik; calcium and integrin binding family member 4; calcium and integrin-binding family member 4; Cib4; KIP4
• Gene Symbols: Cib4
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human CIB4(Accession A0PJX0), corresponding to amino acid residues M141-C185.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 130106
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

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