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  6. Tocris Bioscience™ Cinacalcet hydrochloride
  7. 617050

Tocris Bioscience™ Cinacalcet hydrochloride

Low molecular weight, organic compound that may help regulate biological process.

Supplier:  Tocris Bioscience™ 6170/50

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Catalog No. 61-705-0


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Description

Description

Cinacalcet hydrochloride is a calcium-sensing receptor (CaSR) allosteric agonist. Activates CaSR signaling in cellular proliferation and phosphatidylinositol (PI) hydrolysis assays. Reduces serum parathyroid hormone levels in rats. Also potent CYP2D2 inhibitor (IC50 = 87 nM) and L-type calcium channel blocker. Orally bioavailable.
Specifications

Specifications

Inhibitor
364782-34-3
393.87g/mol
Calcium-Sensing Receptor Agonists
Calcium-Sensing Receptor
C22H22F3N.HCl
Store at -20°C
50 mg
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