Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
CIP2A Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
$151.31 - $568.26
Specifications
Antigen | CIP2A |
---|---|
Applications | Immunofluorescence, Immunohistochemistry |
Classification | Polyclonal |
Conjugate | Unconjugated |
Form | Liquid |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-157-1790
![]() |
Bethyl Laboratories, Inc
IHC00266T |
10 μL |
Each for $151.31
|
|
|||||
50-157-1789
![]() |
Bethyl Laboratories, Inc
IHC00266 |
100 μL |
Each for $568.26
|
|
|||||
Description
The recommended shelf life for this product is 1 year from date of receipt.
Inhibition of protein phosphatase 2A (PP2A) activity has been identified as a prerequisite for the transformation of human cells. The protein, designated Cancerous Inhibitor of PP2A (CIP2A), interacts directly with the oncogenic transcription factor c-Myc, inhibits PP2A activity toward c-Myc serine 62 (S62), and thereby prevents c-Myc proteolytic degradation. In addition to its function in c-Myc stabilization, CIP2A promotes anchorage-independent cell growth and in vivo tumor formation. The oncogenic activity of CIP2A is demonstrated by transformation of human cells by overexpression of CIP2A. Importantly, CIP2A is overexpressed in two common human maligcies, head and neck squamous cell carcinoma (HNSCC) and colon cancer.Specifications
CIP2A | |
Polyclonal | |
Liquid | |
RUO | |
TBS with 0.1% BSA and 0.09% sodium azide | |
Cancerous Inhibitor of Protein Phosphatase 2A , p90 | |
CIP2A | |
IgG | |
Antigen affinity chromatography | |
Antibody |
Immunofluorescence, Immunohistochemistry | |
Unconjugated | |
Rabbit | |
Human | |
Q8TCG1 | |
57650 | |
Between 550 and 600 | |
Primary | |
4° C | |
CIP2A |
Spot an opportunity for improvement?Share a Content Correction
Product Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title