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Cip4 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501986022
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100 μL
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Catalog No. Quantity
50-198-6022 100 μL
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Catalog No. 50-198-6022 Supplier Bioss Supplier No. BS4266R
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Description

Rabbit Polyclonal Antibody

Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.

Specifications

Antigen Cip4
Applications Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Trip10
Gene Accession No. Q15642
Gene Alias AI646975; Cdc42 interacting protein-4; Cdc42-interacting protein 4; CIP4; hSTP; Protein Felic; Salt tolerant protein; salt tolerator; STOT; STP; thyroid hormone receptor interactor 10; Thyroid receptor-interacting protein 10; TR-interacting protein 10; TRIP10; TRIP-10
Gene Symbols Trip10
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Cip4.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9322
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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