Invitrogen™ CIRBP Polyclonal Antibody

Catalog No.	Quantity
PIPA519358	100 μg

Catalog No. PIPA519358 Supplier Invitrogen™ Supplier No. PA519358

Description

Goat Polyclonal Antibody

This antibody is predicted to react with bovine, canine and human based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.

CIRBP is cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. It acts as a translational activator and seems to play an essential role in cold-induced suppression of cell proliferation. It binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. This protein acts as a translational repressor and promotes assembly of stress granules (SGs), when overexpressed.

Specifications

• Antigen: CIRBP
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene: CIRBP
• Gene Accession No.: P60824, P60825, Q14011
• Gene Alias: A18 hnRNP; A18HNRNP; CIRBP; CIRP; cold inducible RNA binding protein; cold inducible RNA-binding protein; cold-inducible RNA-binding protein; glycine-rich RNA binding protein; glycine-rich RNA-binding protein CIRP; R74941; testicular tissue protein Li 39
• Gene Symbols: CIRBP
• Host Species: Goat
• Immunogen: Synthetic peptide sequence (QAGKSSDNRSR) corresponding to the internal amino acids of CIRBP (aa 81-91).
• Purification Method: Ammonium sulfate precipitation
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1153, 12696, 81825
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG