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Invitrogen™ CIRBP Polyclonal Antibody
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Catalog No. PIPA531661
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100 μL
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Catalog No. Quantity
PIPA531661 100 μL
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Catalog No. PIPA531661 Supplier Invitrogen™ Supplier No. PA531661
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HCT116. Predicted reactivity: Mouse (94%), Rat (94%), Chicken (94%), Rhesus Monkey (100%), Chimpanzee (96%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

CIRBP is cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. It acts as a translational activator and seems to play an essential role in cold-induced suppression of cell proliferation. It binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. This protein acts as a translational repressor and promotes assembly of stress granules (SGs), when overexpressed.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CIRBP
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.67 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene CIRBP
Gene Accession No. Q14011
Gene Alias A18 hnRNP; A18HNRNP; CIRBP; CIRP; cold inducible RNA binding protein; cold inducible RNA-binding protein; cold-inducible RNA-binding protein; glycine-rich RNA binding protein; glycine-rich RNA-binding protein CIRP; R74941; testicular tissue protein Li 39
Gene Symbols CIRBP
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human CIRBP. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1153
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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