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Invitrogen™ CIRBP Recombinant Rabbit Monoclonal Antibody (JE55-46)
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Catalog No. PIMA542496
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100 μL
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PIMA542496 100 μL
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Catalog No. PIMA542496 Supplier Invitrogen™ Supplier No. MA542496
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Control: Raji cell lysate, Hela cell lysate, Daudi cell lysate, human thyroid tissue, human colon carcinoma tissue, human prostate carcinoma tissue, human kidney tissue, human pancreas tissue. Subcellular Location: Nucleoplasm, Cytoplasm.

CIRBP is cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. It acts as a translational activator and seems to play an essential role in cold-induced suppression of cell proliferation. It binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. This protein acts as a translational repressor and promotes assembly of stress granules (SGs), when overexpressed.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CIRBP
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone JE55-46
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene CIRBP
Gene Accession No. Q14011
Gene Alias A18 hnRNP; A18HNRNP; CIRBP; CIRP; cold inducible RNA binding protein; cold inducible RNA-binding protein; cold-inducible RNA-binding protein; glycine-rich RNA binding protein; glycine-rich RNA-binding protein CIRP; R74941; testicular tissue protein Li 39
Gene Symbols CIRBP
Host Species Rabbit
Immunogen Recombinant full length protein of Human CIRP.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1153
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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