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CISD2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody
Supplier: Proteintech Group Inc 133181AP150UL

Description
Defects in the CISD2 (CDGSH iron sulfur domain 2) gene are a cause of the neurodegenerative disorder Wolfram syndrome 2. CISD2 is a zinc finger protein that localizes to the endoplasmic reticulum and mitochondria and binds an iron/sulfur cluster. CISD2 interacts with Bcl-2 and can be displaced by the BH3-only protein BIK and contributes to the regulation of BIK-initiated autophagy. CISD2 deficiency in mice causes mitochondrial breakdown accompanied by autophagic cell death as well as the development of premature aging phenotype.Specifications
CISD2 | |
Polyclonal | |
Unconjugated | |
CISD2 | |
CDGSH iron sulfur domain 2, CDGSH2, CISD2, ERIS, Miner1, MitoNEET related 1 protein, NAF 1, WFS2, ZCD2 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
295457, 493856, 67006 | |
-20°C | |
Liquid |
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation | |
0.35 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q8N5K1, Q9CQB5 | |
CISD2 | |
CISD2 Fusion Protein Ag4172 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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