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Invitrogen™ CK1 epsilon Polyclonal Antibody
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Catalog No. PIPA595934
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100 μL
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PIPA595934 100 μL
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Catalog No. PIPA595934 Supplier Invitrogen™ Supplier No. PA595934
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EFSTYLNFCR SLRFDDKPDY SYLRQLFRNL FHRQGFSYDY VFDWNMLKFG AARNPEDVDR ERREHEREER MGQLRGSATR ALPPGPPTGA TANRLRSAAE PVASTPASRI QPAGNTSPRA ISRVDRERKV SMRLHRGAPA NVSSSDLTGR QEVSRIPASQ TSVPFDHLGK; Positive Samples: HeLa, 293T; Cellular Location: Cytoplasm, Nucleus.

CSNK1E (CK1 epsilon) is a serine/threonine kinase implicated in a wide range of cellular functions, including vesicular trafficking, DNA damage repair, cell cycle progression, and cytokinesis. CSNK1E phosphorylate key regulatory proteins involved in the control of cell differentiation, proliferation, chromosome segregation, circadian rhythms, and metabolic pathways. CK1 family members share a highly conserved kinase domain but differ in their variable N-and C-terminal domains. Mammals have seven family members: alpha, beta, gamma1, gamma2, gamma3, delta and epsilon. CKIe positively regulates Akt possibly by inhibiting PP2A. CKIe play an important role in neurodegenerative diseases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CK1 epsilon
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.93 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CSNK1E
Gene Accession No. P49674, Q9JMK2
Gene Alias AI426939; AI551861; AW457082; casein kinase 1; casein kinase 1 epsilon; casein kinase 1, epsilon; casein kinase I isoform epsilon; CK1e; CK1epsilon; CKI, epsilon; CKIe; CKIepsilon; CKI-epsilon; Csnk1e; HCKIE; KC1 epsilon; KC1epsilon; MGC10398; OTTHUMP00000063258; OTTHUMP00000063263; RP1-5O6.1; tau
Gene Symbols CSNK1E
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 247-416 of human CSNK1E (NP_6894071).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1454, 27373, 58822
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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