Invitrogen™ CK1 gamma-1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5121110

Catalog No. PIPA5121110

Description

Positive test controls include: Jurkat, HeLa, 293T, MCF7, A-549. The target is usually found in the following locations: Cytoplasm. Immunogen sequence: FFEKPDYEYL RTLFTDLFEK KGYTFDYAYD WVGRPIPTPV GSVHVDSGAS AITRESHTHR DRPSQQQPLR NQVVSSTNGE LNVDDPTGAH SNAPITAHAE VEVVEEAKCC CFFKRKRKKT AQRHK.

Casein kinase I (also designated CKI) and casein kinase II (also designated CKII) compose a family of serine/ threonine protein kinases which are present in all eukaryotes examined to date. CKI family members, which include CKI alpha, gamma, epsilon and delta, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an alpha2 beta2 or an alpha alpha' beta2 structure. The alpha catalytic subunit is stimulated by the beta regulatory subunit, which undergoes autophosphorylation. CKII activity is high in the cytosol and nucleus of proliferating and differentiating cells. CKII is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.

Specifications

• Antigen: CK1 gamma-1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Csnk1g1
• Gene Alias: 9130020E21Rik; casein kinase 1 gamma 1; casein kinase 1, gamma 1; casein kinase I isoform gamma-1; casein kinase I, gamma 1; CK I gamma1; CK1G1; CK1gamma1; CKI gamma 1; CKI gamma1; CK-I gamma1; CKI- gamma1; CKI gamma-1; CKI-gamma 1; CKI-gamma-1; CSNK1G1; KC1G1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 53944
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.86 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9HCP0
• Gene Symbols: Csnk1g1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 298-422 of human CSNK1G1 (NP_071331.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov