Invitrogen™ CKAP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552556

Catalog No. PIPA552556

Description

Immunogen sequence: PPIRSHHSNT RDTVKQGISR TSANVTIRKG PHEKELLQSK TALSSVKTSS SQGIIRNKTL SRSIASEVVA RPASLSNDKL MEKSEPVDQR RHTAGKAIVD SRSAQPKETS EERKARLSEW KAGKGR Highest antigen sequence identity to the following orthologs: Mouse - 51%, Rat - 49%.

Nedd4-binding partner-1 (N4BP1) is a developmentally expressed protein interactor and monoubiquitylation substrate of Nedd4, a HECT domain-containing ubiquitin ligase that mediates ubiquitylation and proteasome degradation of target proteins and may have a fundamental role to play in embryonic processes. N4BP1 can undergo Nedd4-mediated polyubiquitylation and proteosomal degradation. N4BP1 also functions as a negative regulator of AIF4 (also known as ITCH or Atrophin-1), an E3-ubiquitin ligase, by interacting with the second WW domain of AIF4 and impairing ubiquitination of substrates.

Specifications

• Antigen: CKAP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CKAP2
• Gene Alias: AI461656; AW228814; Ckap2; CTCL tumor antigen se20-10; cytoskeleton associated protein 2; cytoskeleton-associated protein 2; LB1; se20-10; TMAP; Tumor- and microtubule-associated protein; tumor-associated microtubule-associated protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26586
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8WWK9
• Gene Symbols: CKAP2
• Immunogen: Recombinant protein corresponding to Human CKAP2. Recombinant protein control fragment (Product #RP-89675).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG