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Invitrogen™ CKAP2 Polyclonal Antibody
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Catalog No. PIPA552556
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100 μL
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PIPA552556 100 μL
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Catalog No. PIPA552556 Supplier Invitrogen™ Supplier No. PA552556
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PPIRSHHSNT RDTVKQGISR TSANVTIRKG PHEKELLQSK TALSSVKTSS SQGIIRNKTL SRSIASEVVA RPASLSNDKL MEKSEPVDQR RHTAGKAIVD SRSAQPKETS EERKARLSEW KAGKGR Highest antigen sequence identity to the following orthologs: Mouse - 51%, Rat - 49%.

Nedd4-binding partner-1 (N4BP1) is a developmentally expressed protein interactor and monoubiquitylation substrate of Nedd4, a HECT domain-containing ubiquitin ligase that mediates ubiquitylation and proteasome degradation of target proteins and may have a fundamental role to play in embryonic processes. N4BP1 can undergo Nedd4-mediated polyubiquitylation and proteosomal degradation. N4BP1 also functions as a negative regulator of AIF4 (also known as ITCH or Atrophin-1), an E3-ubiquitin ligase, by interacting with the second WW domain of AIF4 and impairing ubiquitination of substrates.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CKAP2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CKAP2
Gene Accession No. Q8WWK9
Gene Alias AI461656; AW228814; Ckap2; CTCL tumor antigen se20-10; cytoskeleton associated protein 2; cytoskeleton-associated protein 2; LB1; se20-10; TMAP; Tumor- and microtubule-associated protein; tumor-associated microtubule-associated protein
Gene Symbols CKAP2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CKAP2. Recombinant protein control fragment (Product #RP-89675).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26586
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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