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CKAP2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987978
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100 μL
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50-198-7978 100 μL
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Catalog No. 50-198-7978 Supplier Bioss Supplier No. BS7745R
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Rabbit Polyclonal Antibody

Nedd4-binding partner-1 (N4BP1) is a developmentally expressed protein interactor and monoubiquitylation substrate of Nedd4, a HECT domain-containing ubiquitin ligase that mediates ubiquitylation and proteasome degradation of target proteins and may have a fundamental role to play in embryonic processes. N4BP1 can undergo Nedd4-mediated polyubiquitylation and proteosomal degradation. N4BP1 also functions as a negative regulator of AIF4 (also known as ITCH or Atrophin-1), an E3-ubiquitin ligase, by interacting with the second WW domain of AIF4 and impairing ubiquitination of substrates.

Specifications

Antigen CKAP2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene CKAP2
Gene Accession No. Q8WWK9
Gene Alias CKAP2; CTCL tumor antigen se20-10; cytoskeleton associated protein 2; Cytoskeleton-associated protein 2; LB1; se20-10; TMAP; Tumor- and microtubule-associated protein; tumor-associated microtubule-associated protein
Gene Symbols CKAP2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human CKAP2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26586
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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